Inflection Point of Drug Formulation: Advanced in Silico Applications for Rational Drug Development

Industry Roundtable Sponsored by Catalent

Date/Time: Monday, July 23, 2018 - 1:30 PM to 3:30 PM


Drug formulation is largely an empirical method that requires significant time, material, and labor. The next generation of drug delivery approaches, which need to overcome both physicochemical and biological barriers, will be found at the intersection of thorough understanding of biological mechanisms, incorporating pharmacokinetic and formulation considerations during drug molecule design, deciphering material chemistry, and advanced computer modeling. Harnessing the power of in silicomodeling and simulation technologies along with in vitro studies will subtly shift the old ways of drug formulation, but cause profound impact. The result will be faster development, less attrition, reduced costs, and most importantly, better treatments for patients.

Moderated by: Ronak Savla, Pharm.D., Ph.D. Scientific Affairs Manager, Catalent

Invited Speakers:

Simulation and Modeling Drug-Polymer Interaction and Drug Transport/Release through Excipient Polymer Gels
Ronald G. Larson, George Granger Brown Professor, A.H. White Distinguished University Professor, Department of Chemical Engineering, University of Michigan  -

Integrated pharmacokinetic modelling to guide formulation development
Jan Neelissen, Scientific Adviser, Catalent Pharma Solutions